Better IVF

Research

Studies that matter for women over 38, explained and tagged by topic.

Browse by stage of the IVF funnel

Studies

8 studies
Transfer
Age 40+

Natural-cycle FET beats medicated, even over 40

Natural preparation gave higher ongoing-pregnancy rates than HRT for euploid embryos.

1.5x Oddshigher ongoing pregnancy
Testing
Euploidy

Five euploid transfers reach 96 to 99% live birth

Across 123,987 patients, this study found true recurrent implantation failure was under 2%.

96 to 99.6%live birth after five transfers
▷ InteractiveEggs
HGHAge 40+

Growth hormone lifts live-birth odds in women over 40

Pooled trials show higher clinical-pregnancy and live-birth odds with growth hormone in women over 40.

4.12xhigher live-birth odds, 40+
Transfer
Iron

Correcting low ferritin roughly doubled live birth

An iron infusion for ferritin at or below 30 raised live birth, even with normal haemoglobin.

26% → 51%live birth rate after iron infusion
Sperm
MicrofluidicAge 40+

Microfluidic sperm selection beats swim-up

The SwimCount Harvester delivered better sperm and more usable blastocysts than swim-up.

40.5%usable blastocyst rate (vs 34.5% swim-up)
Fertilise
Adjunct

Calcium ionophore: proven for failed fertilisation

Assisted oocyte activation roughly doubled pregnancy and live birth when fertilisation had failed.

2xlive birth rate
Testing
Mosaicism

Mosaic embryos, ranked: which to transfer first

1,000 transfers show mosaics work, and which types give the best chance at a live birth.

1,000mosaic transfers ranked
▷ InteractiveSperm
PICSIAge 40+

Selecting sperm by hyaluronan binding cut miscarriage

In the HABSelect trial, PICSI cut miscarriage from 7.0% to 4.3%, with the benefit concentrated in older women.

7.0% → 4.3%miscarriage, a 39% relative drop